Letrozole
- Model: steroid-58
- 1000 Kilogram in Stock
Company Name: Shanghai MeiHua
Certification: ISO9001, SGS, KOSHER
Delivery Time: 5~8 working days
Delivery Way: Domestic Delivery in Canada, Europe
Payment Terms: T/T, Western Union, Bitcoin
Email: sale@getraws.com
Details:
Trade Name: Femara
CAS NO: 112809-51-5
Color: White Crystalline Powder
Use: Human Growth Peptide
Appearance: White Power
Delivery Time: 5-7 Working Days
Molecular Weight: 285.3
Assay: 99%Min
Minimum Order Quantity: 10 Grams
Molecular Formula: C17H11N5
Suitable for: Adult
Transport Package: Foil Bag or Send by Discreet Parcel
To Be Better
- Domestic Shipping Method. If you need domestic delivery service, we can ship it to you directly in your country from Canada. We have enough stocks in there and domestic delivery countries including USA, UK, Germany, Italy, France, etc.
- Concentration. We specialized in manufacturing and exporting best high quality raw steroid powders for more than 10 years. Our products now have widely appreciated by customers in Canada, USA, France, Germany and others.
- Discreet Packing Methods. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels.
- Fast Delivery. Sufficient stock & disciplined packing team to make sure prompt and discreet delivery. Customs pass rate ≥99%.
Basic Information about Femara Letrozole
Femara, sold under the brand name Femara, is a prescription drug used to treat breast cancer in its advanced stages, and in women who have finished menopause. Doctors may use Femara off-label in fertility treatments to help encourage egg release (ovulation) in women. Femara belongs to a class of cancer drugs known as aromatase inhibitors, which work by preventing the body from converting a hormone called androgen into estrogen.
Characteristic Analysis Report for Femara Letrozole
TEST ITEMS |
SPECIFICATION
|
RESULTS
|
Description |
White Crystalline Powder |
White Powder |
Identification |
Positive |
Positive |
Assay(by HPLC) |
98.0~102.0% |
99.58% |
Absorbance(E1cm) |
465~495 |
486.5 |
Melting Point |
191~195ºC |
192.5~195.0ºC |
Loss On Drying |
0.5%max |
0.22% |
Specific Rotation |
+288º~ +298º |
+295.2ºC |
Residue On Ignition |
0.1%max |
0.02% |
Related Substances |
Total:1.5%max |
<1.2% |
|
Single:0.5%max |
<0.6% |
Residue Solvents |
0.2%max |
0.1% |
Heavy Metals |
20PPm max |
<10PPm |
Functions of Femara Letrozole
Letrozole is used for treating postmenopausal women with breast cancer. The growth of some breast cancers in postmenopausal women is promoted by estrogens that circulate in the blood, and the adrenal glands are the main source of these circulating estrogens. Letrozole inhibits the enzyme in the adrenal glands (aromatase) that produces the estrogens, estradiol and estrone. Letrozole was approved by the FDA in 1997.
Relationship between Femara Letrozole and Tamoxifen
Tamoxifen is also used to treat hormonally-responsive breast cancer, but it does so by interfering with the estrogen receptor. However, letrozole is effective only in post-menopausal women, in whom estrogen is produced predominantly in peripheral tissues (i.e. in adipose tissue, like that of the breast) and a number of sites in the brain. In pre-menopausal women, the main source of estrogen is from the ovaries not the peripheral tissues, and letrozole is ineffective.
In the BIG 1-98 Study, of post-menopausal women with hormonally-responsive breast cancer, letrozole reduced the recurrence of cancer, but did not change survival rate, compared to tamoxifen.
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