Details: 
 
CAS:  521-18-6
  Synonyms:  Androstanolone
  Molecular  Formula: C19H30O2
  Molecular  Weight: 290.44g/mol
  Melting  Point: 178-183 ºC
  Suitable  for: Adult
  Appearance:  White Crystal Powder
  State:  Solid
  Assay:  99% Min
  Certification:  GMP, HSE, ISO 9001, USP
 
Descriptions  about Stanolone
  Dihydrotestosterone  (DHT), or 5α-dihydrotestosterone (5α-DHT), also known as androstanolone or  stanolone, is an endogenous androgen sex steroid and hormone. The enzyme  5α-reductase catalyzes the formation of DHT from testosterone in certain  tissues including the prostate gland, seminal vesicles, epididymides, skin,  hair follicles, liver, and brain. This enzyme mediates reduction of the C4-5  double bond of testosterone. Relative to testosterone, DHT is considerably more  potent as an agonist of the androgen receptor (AR).
 
Stanolone's  Medical Uses
  Stanolone  is available in pharmaceutical formulations for medical use as an androgen or  anabolic-androgenic steroid. It is used mainly in the treatment of male  hypogonadism. When used as a medication, dihydrotestosterone is referred to as  androstanolone or as stanolone, and is sold under brand names such as Andractim  among others. The availability of pharmaceutical DHT is limited; it is not  available in the United States or Canada, but is available in certain European  countries. The available formulations of DHT include buccal or sublingual  tablets, topical gels, and, as esters in oil, injectables like  dihydrotestosterone propionate and dihydrotestosterone valerate.
 
Stanolone's  Importance During Sexual Development
  During  male embryogenesis stanolone has an essential role in the formation of the male  external genitalia, while in the adult male stanolone acts as the primary  androgen in the prostate gland, seminal vesicles, skin, and hair follicles.
  An  example illustrating the significance of stanolone for the development of  secondary sex characteristics is congenital 5α-reductase type II deficiency.  This genetic mutation can result in pseudohermaphroditism. The condition  typically presents with underdeveloped male genitalia and prostate. Males with  this condition are often raised as girls due to their lack of conspicuous male  genitalia. At the onset of puberty, although their DHT levels remain very low,  their testosterone levels elevate normally. Their musculature develops like  that of other male adults. After puberty, men with this condition have a large  deficiency of pubic and body hair and reportedly no incidence of androgenic  alopecia (pattern hair loss).They also reportedly have no incidence of prostate  cancer.
Unlike  other androgens such as testosterone, DHT cannot be converted by the enzyme  aromatase into an estrogen like estradiol. Therefore, it is frequently used in  research settings to distinguish between the effects of testosterone caused by  binding to the AR and those caused by testosterone's conversion to estradiol  and subsequent binding to and activation of estrogen receptors.
 
Effect  of Stanolone
  Stanolone  can be used as pharmaceutical material. Its main function is to promote  metabolism. Anabolic effects include growth of muscle mass and strength,  increased bone density and strength, and stimulation of linear growth and bone  maturation. It doesn't metabolize in the body long enough to make it to the  muscles.
  The  main androgen which is secreted by the testes is of course testosterone.  However, in most of the body, the androgenic sign is not carried through by  testosterone. In these tissues including brain (CNS), skin, genitals -  practically everything but muscle - the active androgen is actually  dihydrotestosterone (DHT).
Stanolone  is use for chronic wasting disease, osteoporosis, severe infection and trauma,  burn, etc caused by the negative nitrogen balance, promote the growth of  premature infants and immature, etc. The fracture is not easy to heal.  Hypercholesterolemia and postpartum depression can also be used.
 
Basic  Test For Stanolone
 
  
    | Description   | White    Powder  | 
  
    | Tests  | Analysis Standard  | Results  | 
  
    | Identification  | Conform  | Conform  | 
  
    | Heavy    metals  | ≤10    ppm  | Conform  | 
  
    | Specific    Rotation  | +27º | +27º  | 
  
    | Chromatography    Purity  | Conform  | Conform  | 
  
    | Melting    point  | 173~    183ºC  | 174.5~182.2ºC  | 
  
    | Organic    Volatile Impurities  | Conform  | Conform  | 
  
    | Loss    On Drying  | ≤0.5%  | 0.15%  | 
  
    | Residue    On Ignition  | 0.1%max  | 0.06%  | 
  
    | Assay  | 98.0%min  | 99.18%  | 
 
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